Topoisomerase the Deena

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Topoisomerase
100% Happy
Owner
twinkle
Stolen
29 Aug 2023
Hatched
7 Sep 2023
Immortal
7 Oct 2023
6,457 +1
Views
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π™²πš›πšŽπšŠπšπšžπš›πšŽ π™Ώπš›πš˜πšπš’πš•πšŽ: πšƒπš˜πš™πš˜πš’πšœπš˜πš–πšŽπš›πšŠπšœπšŽ


Topoisomerase

- is an enzyme that plays a role in DNA replication & repair by unwinding DNA strands. They sense & regulate DNA supercoiling, which is essential for proper DNA functioning.

It has two primary types:

Topoisomerase I - alleviates the torsional stress in DNA by inducing temporary single-strand breaks in the DNA. This enables rotation & relaxation of DNA strands to facilitate DNA replication and transcription.

Topoisomerase II - separates intertwined DNA strands and creates temporary double-strand breaks in the DNA, allowing the DNA strands to pass through each other.

In cancer treatment, topoisomerases are targeted because of their crucial role in DNA replication. By inhibiting their activity, DNA strands become trapped in a state of overwinding or underwinding, resulting in DNA damage and cell death. Topoisomerase inhibitors is a drug class to specifically target these enzymes and are used in chemotherapy.

Topoisomerase inhibitors may be used in the treatment of colorectal cancer, breast cancer and leukemia.
Topoisomerase I inhibitors - Camptothecins: irinotecan, topotecan
Topoisomerase II inhibitors - Epipodophyllotoxins: etoposide, teniposide; Anthracyclines (doxorubicin, epirubicin)


π™ΏπšŽπš π™Έπš—πšπš˜πš›πš–πšŠπšπš’πš˜πš—


β™‘ personally bought from the SARC for 10 million EC!~
β™‘ this creature belongs to πŸ†ƒπŸ††πŸ…ΈπŸ…½πŸ…ΊπŸ…»πŸ…΄ ⭐

About Deena Eggs

Oh my! This egg looks like a collection of mitochondria, DNA, and other mysterious organelles!

About the Deena Creature

Deenas are the most elemental of creatures: they are literally living strands of DNA. Deenas are thought by the Science and Research Center in Ark City to be all-knowing about the mysteries of DNA, what it does, and how it can be fixed when its broken. For the purposes of health research, Deenas are being studied extensively.

Deenas also have the ability to change your DNA on the spot. Don't like your hair or eye color? Find a Deena and they can change it for you! Want to be shorter or taller? A Deena might have a solution for you. Since Deenas have arrived onto the scene, thousands of Arkians have experimented with changing themselves. Some Arkians are even trying to alter their own creatures themselves.

While not illegal, note that the process of changing your DNA is entirely unregulated by the Town Hall in Ark City. The repercussions of altering your own DNA are unknown and could lead to unwanted mutations and catastrophic health consequences.