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RNAsplicing the Sorrowool

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truffle

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11 May 2023

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22 Dec 2023

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Eukaryotic cells modify mRNA after transcription.

Capping: addition of methyl group to the 5’-end of mRNA to prevent degradation by exonucleases and allows it to be recognised by the cell’s translational machinery.
Splicing: the removal of introns (intruding sequences) so that exons (expressing sequences) can fuse together to form a continuous sequence.
Polyadenylation: addition of a long chain of adenine nucleotides to the 3’-end. Improves stability and facilitates export from the nucleus.

Splicing of mRNA increases the number of different proteins an organism can produce.

Alternative splicing: can also result in the removal of exons (alternative splicing). This means different polypeptides can result from a single gene sequence.

About Sorrowool Eggs

A storm cloud resembling that of a waterlogged cotton ball may soon reveal itself to be a Sorrowool egg amidst a nest of many.

About the Sorrowool Creature

Sorrowool herds typically gather high above farmlands to quench thirsty crops during times of severe drought. Farmers blessed by the joyous tears of these sheep showers yield plentiful bounties come harvest season.

The Sorrowool is not mournful, but grateful. The all-encompassing beauty of nature is what moves the Sorrowool to tears and they share this appreciation with the lands below.